Aliases
CDC25M3; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P30304
NCBI Gene ID: 993
Immunogen
Synthesized non-phosphopeptide derived from human CDC25A around the phosphorylation site of serine 178 (Q-N-S(p)-A-P).
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.Galaktionov K.I.,Cell 67:1181-1194(1991).The MGC Project Team;Genome Res. 14:2121-2127(2004).Wegener S., Eur. J. Cell Biol. 79:810-815(2000).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
