Aliases
KIF10; CENP-E; PPP1R61
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: Q02224
NCBI Gene ID: 1062
Gen
Immunogen
Synthetic peptide corresponding to residues near the N terminal of human centromere protein E, 312kDa
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500-1:2000, Immunohistochemistry: 1:50-1:200
Background / Function
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified