Aliases
centrosomal protein of 57 kDa; FGF2-interacting protein; PIG8; testis-specific protein 57; translokin
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q86XR8
NCBI Gene ID: 9702
Immunogen
Synthesized peptide derived from internal of human CEP57.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.Bossard C., Nat. Cell Biol. 5:433-439(2003).Nagase T., DNA Res. 2:37-43(1995).Ota T., Nat. Genet. 36:40-45(2004)
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
