Aliases
Choline/ethanolamine kinase; Choline kinase beta (EC 2.7.1.32)(CK); Ethanolamine kinase (EC 2.7.1.82)(EK); CHKB; CHETK
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q9Y259
NCBI Gene ID: 1120
Immunogen
Synthesized peptide derived from internal of human CHKB.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis.Yamazaki N., J. Biol. Chem. 275:31739-31746(2000).Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).Yu L.-R., J. Proteome Res. 6:4150-4162(2007).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
