Cleaved-PARP antibody

$443.21$444.31

SKU: 11317 Categories: ,

Description

Aliases

ADP-ribosyltransferase 1; ADPRT; ADPRT1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) pol; poly [ADP-ribose] polymerase 1; poly[ADP-ribose] synthetase 1; PPOL

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot#: P09874

Raised In

Rabbit

Species Reactivity

Human Mouse

Tested Applications

WB Recommended dilution: WB: 1:500-1:2000

Background / Function

Nvolved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Conjugate

Unconjugated

Storage Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 14 months from date of receipt

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antigen Affinity Purified

Additional information

Size

100μl

Certificate of Analysis