Aliases
cystain-SA-I; cystatin-1; cystatin-SN; CYTN; salivary cystatin-SA-1
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P01037
NCBI Gene ID: 1469
Immunogen
Synthesized peptide derived from internal of human CST1.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
IHC IF Recommended dilution: Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:500
Background / Function
Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.Deloukas P., Nature 414:865-871(2001).Zhang Z., Protein Sci. 13:2819-2824(2004).Dickinson D.P., DNA Cell Biol. 21:47-65(2002).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
