Aliases
HP1; MRS; DEF1; HP-1; DEFA2; HNP-1/HP3; DEF3; HNP3; HP-3; HNP-3
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: P59665/P59666
NCBI Gene ID: 1667/
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human defensin, alpha 1/3
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
IHC Recommended dilution: Immunohistochemistry: 1:25-1:100
Background / Function
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Defensin, alpha Several alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
