Description
Aliases
Axonemal beta dynein heavy chain 3, HsADHC3, Ciliary dynein heavy chain 3, Dnahc3-b, DNAHC3B, DNAH3
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q8TD57
Immunogen
Recombinant human Dynein heavy chain 3, axonemal protein (1-150AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Dynein heavy chain 3, axonemal protein
Literature
[1]”DNAH3: characterization of the full length gene and mutation search in patients with primary ciliary dyskinesia.” Blouin J.-L., Gehrig C., Jeganathan D., Bartoloni L., Rossier C., Duriaux Sail G., Scamuffa N., Mitchison H.M., DeLozier Blanchet C.D., Antonarakis S.E. Submitted (MAR-2002). [2]”Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S. Nat. Genet. 36:40-45(2004). [3]”The consensus coding sequences of human breast and colorectal cancers.” Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. Velculescu V.E. Science 314:268-274(2006).Additional information
| Size | 50μg, 100μg |
|---|
