Aliases
Double C2-like domain-containing protein betaDoc2-beta, DOC2B, DOC2BL
Antibody Type
Polyclonal
Species
Human
Uniprot ID
Q14184
Immunogen
Recombinant Human Double C2-like domain-containing protein beta protein (7-180AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA
Background / Function
Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity).
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Modification
Double C2-like domain-containing protein beta
