Aliases
Transcription factor COE2, Early B-cell factor 2, EBF-2, EBF2, COE2
Antibody Type
Polyclonal
Species
Human
Uniprot ID
Q9HAK2
Immunogen
Recombinant human Transcription factor COE2 protein (53-254AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5′-ATTCCCNNGGGAATT-3′ (By similarity).
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Modification
Transcription factor COE2
