Aliases
ETS-domain transcription factor ERF; Ets2 repressor factor;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P50548
NCBI Gene ID: 2077
Immunogen
Synthesized peptide derived from internal of human ERF.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
IHC Recommended dilution: Immunohistochemistry: 1:50~1:100
Background / Function
Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment By similarity. May be important for regulating trophoblast stem cell differentiation By similarity.Sgouras D.N., EMBO J. 14:4781-4793(1995).Grimwood J., Nature 428:529-535(2004).Olsen J.V., Cell 127:635-648(2006).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
