Aliases
G0/G1 switch protein 2, G0/G1 switch regulatory protein 2, Putative lymphocyte G0/G1 switch gene, G0S2
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P27469
Immunogen
Recombinant human G0/G1 switch protein 2 protein (1-103AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]”Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2.”Welch C., Santra M.K., El-Assaad W., Zhu X., Huber W.E., Keys R.A., Teodoro J.G., Green M.R.Cancer Res. 69:6782-6789(2009). [2]”The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”The MGC Project TeamGenome Res. 14:2121-2127(2004). [3]”The DNA sequence and biological annotation of human chromosome 1.” Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. Bentley D.R. Nature 441:315-321(2006).
