General Description
Glycine is a non-essential, non-polar, non-optical, glucogenic amino acid.
Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Application:
Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.
CAS Number:Â Â Â Â Â Â Â Â Â 56-40-6;
Synonyms:Â Â Â Â Â Â Â Â Â Â Â 2-Aminoacetic acid; Aminoacetic acid; Glycocoll; Aminoethanoic acid
Molecular Formula:Â Â Â C2H5NO2;
Molecular Weight:Â Â Â Â 75.067 g/mol
InChI Key:Â Â Â Â Â Â Â Â Â Â Â DHMQDGOQFOQNFH-UHFFFAOYSA-N
