Description
Aliases
Guca2b
Antibody Type
Polyclonal Antibody
Species
Mouse
Uniprot ID
O09051
Immunogen
Recombinant mouse Guanylate cyclase activator 2B protein (22-106AA)
Raised In
Rabbit
Species Reactivity
Mouse
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]Uroguanylin and guanylin: distinct but overlapping patterns of messenger RNA expression in mouse intestine. Whitaker T.L., Witte D.P., Scott M.C., Cohen M.B. Gastroenterology 113:1000-1006(1997). [2]Sanford L.P., Cohen M.B.Submitted (FEB-2000).Additional information
Size | 50μg, 100μg |
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