Aliases
3-hydroxyisobutyrate dehydrogenase; mitochondrial; EC 1.1.1.31; HIBADH;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P31937
NCBI Gene ID: 11112
Immunogen
Synthesized peptide derived from C-terminal of human HIBADH.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
IHC Recommended dilution: Immunohistochemistry: 1:50~1:100
Background / Function
This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.Hillier L.W., Nature 424:157-164(2003).Hughes G.J., Electrophoresis 14:1216-1222(1993).Structural genomics consortium (SGC); Submitted (APR-2006) to the PDB data bank.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
