Aliases
HLA class II histocompatibility antigen, DM alpha chain, HLA-DMA, DMA, RING6, MHC class II antigen DMA, Really interesting new gene 6 protein
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P28067
Immunogen
Recombinant human HLA class II histocompatibility antigen, DM alpha chain protein (27-233AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC;Not yet tested in other applications.
Background / Function
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
