Aliases
EC 2.7.10.2; JAK-1; JAK1; JAK1A; Janus kinase 1
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P23458
NCBI Gene ID: 3716
Immunogen
Synthesized peptide derived from internal of human JAK1.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
IHC IF Recommended dilution: Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:500
Background / Function
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.Wilks A.F., Mol. Cell. Biol. 11:2057-2065(1991).Lee S.-T., Oncogene 8:3403-3410(1993).Lindholm C.K., Biochem. Biophys. Res. Commun. 296:929-936(2002).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
