Description
Aliases
JAK-2; JAK2; Janus kinase 2; kinase Jak2;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: O60674
NCBI Protein: NP_004963.1
Immunogen
Peptide sequence around phosphorylation site of tyrosine 1007 (K-E-Y(p)-Y-K) derived from Human JAK2.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC Recommended dilution: Predicted MW: 125kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,
Background / Function
Plays a role in leptin signaling and control of body weightJames C, et al. (2005) Nature. 434(7037): 1144-1148.Argetsinger LS, et al. (2004) Mol Cell Biol. 24(11): 4955-4967.Ungureanu D, et al. (2002) Mol Cell Biol. 22(10): 3316-3326.Xie S, et al. (2001) Oncogene. 20(43): 6188-6195.
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Tyr1007
Additional information
| Size | 100μl |
|---|
