Aliases
MAP2A; MAP2B; MAP2C
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P11137
NCBI Protein: NP_002365.3
Immunogen
Peptide sequence around aa.1819~1823 (T-A-A-L-A) derived from Human MAP2.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IF Recommended dilution: Predicted MW: 55-75(2c/2d), 280(2a/2b)kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Background / Function
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. DeGiorgis J.A., Jaffe H., Moreira J.E., Carlotti C.G. Jr. Proteome Res. 4:306-315(2005)Olsen J.V., Blagoev B., Gnad F., Macek B. Mann M.Cell 127:635-648(2006)Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. Science 316:1160-1166(2007)
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
