Aliases
P38B; SAPK2; p38-2; PRKM11; SAPK2B; p38Beta; P38BETA2
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: Q15759
NCBI Gene ID: 5600
Gen
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human mitogen-activated protein kinase 11
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500-1:2000, Immunohistochemistry: 1:25-1:100
Background / Function
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. [
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
