Aliases
MART-1; MART1; melan-A; MELAN A; MELANOMA ANTIGEN RECOGNIZED BY T CELLS 1
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q16655
NCBI Gene ID: 2315
Immunogen
Synthesized peptide derived from human MART-1.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500~1:3000, Immunohistochemistry: 1:50~1:100,
Background / Function
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.Toshihiko Hoashi, J. Biol. Chem., Apr 2005; 280: 14006 – 14016. Maria P. Bettinotti, J. Immunol., Jul 1998; 161: 877. P. J. Frost, J. Immunol., Mar 2001; 166: 3564. Flora Wang, Clin. Cancer Res., Oct 1999; 5: 2756.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
