Aliases
Myc-associated zinc finger protein; MAZI; Purine-binding transcription factor; Pur-1; ZF87
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P56270
NCBI Gene ID: 4150
Immunogen
Synthesized peptide derived from internal of human MAZ.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.Bossone S.A., Proc. Natl. Acad. Sci. U.S.A. 89:7452-7456(1992).Pyrc J.J., Biochemistry 31:4102-4110(1992).Tsutsui H., Biochem. Biophys. Res. Commun. 226:801-809(1996).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
