Aliases
hPK38; KIAA0175; hMELK
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q14680
NCBI Protein: NP_055606.1
Immunogen
Peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
WB Recommended dilution: Predicted MW: 74kd, Western blotting: 1:500
Background / Function
Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis. Seong H.-A., Gil M., Kim K.-T., Kim S.-J., Ha H. Biochem. J. 361:597-604(2002) Vulsteke V., Beullens M., Boudrez A., Keppens S. Biol. Chem. 279:8642-8647(2004)
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
