Aliases
EC 3.1.3.62; inositol (1; 3; 4; 5)-tetrakisphosphate 3-phosphatase
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q9UNW1
NCBI Gene ID: 9562
Immunogen
Synthesized peptide derived from internal of human MINPP1.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).Caffrey J.J., FEBS Lett. 442:99-104(1999).Chi H., Genomics 56:324-336(1999).Wiemann S., Genome Res. 11:422-435(2001).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
