Aliases
Macrophage elastase Matrix metalloproteinase-12 MMP12 HME
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P39900
Immunogen
Recombinant human Macrophage metalloelastase protein (109-470AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1′ site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Cancer
Literature
[1]Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages.Shapiro S.D., Kobayashi D.K., Ley T.J.J. Biol. Chem. 268:23824-23829(1993) [2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., M
