Aliases
MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: P51512
NCBI Gene ID: 4325
Gen
Immunogen
Fusion protein corresponding to a region derived from internal residues of human matrix metallopeptidase 16 (membrane-inserted)
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
IHC Recommended dilution: Immunohistochemistry: 1:50-1:200
Background / Function
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
