Description
Aliases
Nascent polypeptide-associated complex subunit alpha-2, Alpha-NAC-like, Hom s 2.01, Nascent polypeptide-associated complex subunit alpha-like, NAC-alpha-like, NACA2, NACAL
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9H009
Immunogen
Recombinant human Nascent polypeptide-associated complex subunit alpha-2 protein (1-215AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Additional information
Size | 50μg, 100μg |
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