Aliases
KIAA1047; N-CoR1;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: O75376
NCBI Gene ID: 9611
Immunogen
Synthesized peptide derived from Internal of human NCoR1.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500~1:3000, Immunohistochemistry: 1:50~1:100,
Background / Function
Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6.Igor Girault, Clin. Cancer Res., Apr 2003; 9: 1259. Xinjian Peng, Carcinogenesis, May 2007; 28: 1000 – 1007. Satoshi Mikawa, Genome Res., May 2007; 17: 586 – 593. Claire M. Banwell, Clin. Cancer Res., Apr 2006; 12: 2004 – 2013.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.