Description
Aliases
GRIN2B; NMDE2; NME2; NR2B; NR3
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q13224
NCBI Protein: NP_000825.2
Immunogen
Peptide sequence around phosphorylation site of Tyr1474 (H-V-Y(p)-E-K) derived from Human NMDAR2B.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IF Recommended dilution: Predicted MW: 190kdWestern Blot: 1:500~1000, Immunofluorescence: 1:100~1:200
Background / Function
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Babb TL et al.Epilepsy Res. 2005 Mar-Apr;64(1-2):23-30 Chazot PL. Curr Med Chem. 2004 Feb;11(3):389-96 Kakegawa W, et al.Eur J Neurosci. 2003 Feb;17(4):887-91
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Tyr1474
Additional information
| Size | 100?l |
|---|
