Aliases
Pro-neuregulin-2, membrane-bound isoform, Pro-NRG2Cleaved into the following chain:Neuregulin-2, NRG-2, NRG2, NTAK, Divergent of neuregulin-1, DON-1, Neural- and thymus-derived activator for ERBB kinases, NTAK
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
O14511
Immunogen
Recombinant human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, WB, IHC;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200
Background / Function
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
