Description
Aliases
ORF3
Antibody Type
Polyclonal Antibody
Species
Hepatitis E virus genotype 1
Uniprot ID
O90299
Immunogen
Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA)
Raised In
Rabbit
Species Reactivity
Hepatitis E virus genotype 1
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
May act as a viral regulatory protein involved in the modulation of mitogenic signaling pathways. May be involved in virion morphogenesis and viral pathogenesis. Expedites the processing and secretion of AMBP from the hepatocyte.
Isotype
IgG
Conjugate
HRP
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]The ORF3 protein of hepatitis E virus interacts with hemopexin by means of its 26 amino acid N-terminal hydrophobic domain II. Ratra R., Kar-Roy A., Lal S.K. Biochemistry 47:1957-1969(2008). [2]The ORF3 protein of hepatitis E virus interacts with liver-specific alpha1-microglobulin and its precursor alpha1-microglobulin/bikunin precursor (AMBP) and expedites their export from the hepatocyte. Tyagi S., Surjit M., Roy A.K., Jameel S., Lal S.K. J. Biol. Chem. 279:29308-29319(2004). [3]The phosphorylated form of the ORF3 protein of hepatitis E virus interacts with its non-glycosylated form of the major capsid protein, ORF2. Tyagi S., Korkaya H., Zafrullah M., Jameel S., Lal S.K. J. Biol. Chem. 277:22759-22767(2002).Additional information
| Size | 50μg, 100μg |
|---|
