Aliases
Orthodenticle homolog 2, OTX2
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P32243
Immunogen
Recombinant human Homeobox protein OTX2 protein (1-297AA)
Raised In
Rabbit
Species Reactivity
Human,Mouse,Zebrafish
Tested Applications
ELISA, WB, IHC;Not yet tested in other applications.
Background / Function
Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5′-TCTAATCCC-3′.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Epigenetics and Nuclear Signaling
Literature
[1]”A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency.”Ashkenazi-Hoffnung L., Lebenthal Y., Wyatt A.W., Ragge N.K., Dateki S., Fukami M., Ogata T., Phillip M., Gat-Yablonski G.Hum. Genet. 127:7
