Aliases
Serine/threonine-protein phosphatase PGAM5, mitochondrial, Bcl-XL-binding protein v68, Phosphoglycerate mutase family member 5, PGAM5
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q96HS1
Immunogen
Recombinant human Serine/threonine-protein phosphatase PGAM5, mitochondrial protein (30-223AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC, IF;Recommended dilution:IHC:1:20-1:200, IF:1:50-1:200
Background / Function
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Modification
Serine/threonine-protein phosphatase PGAM5, mitochondrial
