Description
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P00558
Immunogen
Recombinant human Phosphoglycerate kinase 1 protein (25-417AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Also known as ATP:3-phosphoglycerate 1-phosphotransferase, this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. In addition to its role as a glycolytic enzyme, PGK-1 appears to acts as a polymerase alpha cofactor protein. Defects in PGK1 are generally associated with chronic hemolytic anemia.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Phosphoglycerate kinase 1 protein
Research
Metabolism
Literature
[1] “Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase.”Michelson A.M., Markham A.F., Orkin S.H.Proc. Natl. Acad. Sci. U.S.A. 80:472-476(1983) [2] “Structure of the human phosphoglycerate kinaAdditional information
| Size | 50μg, 100μg |
|---|
