Description
Aliases
Drosophila retinal degeneration B homolog, Phosphatidylinositol transfer protein, membrane-associated 1, Pyk2 N-terminal domain-interacting receptor 2, DRES9, NIR2, PITPNM, PITPNM1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
O00562
Immunogen
Recombinant human Membrane-associated phosphatidylinositol transfer protein 1 protein (1-238AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes.Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Membrane-associated phosphatidylinositol transfer protein 1 protein
Research
Transport
Literature
[1] “A mammalian homologue of the Drosophila retinal degeneration B gene: implications for the evolution of phototransduction mechanisms.”Rubboli F., Bulfone A., Bogni S., Marchitiello A., Zollo M., Borsani G., Ballabio A., Banfi S.Genes FunctAdditional information
Size | 50μg, 100μg |
---|