Aliases
PROS, PROS1
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P07225
Immunogen
Recombinant human Vitamin K-dependent protein S protein (42-676AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]”Intracerebral mass bleeding in a term neonate: manifestation of hereditary protein S deficiency with a new mutation in the PROS1 gene” Fischer D., Porto L., Stoll H., Geisen C., Schloesser R.L. Neonatology 98:337-340(2010). [2]”The consensus coding sequences of human breast and colorectal cancers.” Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list Velculescu V.E. Science 314:268-274(2006). [3]”Molecular diversity and thrombotic risk in protein S deficiency: the PROSIT study.” Protein S Italian team (PROSIT) Biguzzi E., Razzari C., Lane D.A., Castaman G., Cappellari A., Bucciarelli P., Fontana G., Margaglione M., D’Andrea G., Simmonds R.E., Rezende S.M., Preston R., Prisco D., Faioni E.M. Hum. Mutat. 25:259-269(2005).
