Aliases
PH and SEC7 domain-containing protein 4, PSD4, EFA6B, TIC, Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B, Exchange factor for ARF6 B, Pleckstrin homology and SEC7 domain-containing protein 4, Telomeric of interleukin-1 cluster protein
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q8NDX1
Immunogen
Recombinant human PH and SEC7 domain-containing protein 4 protein (1-300AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
