Aliases
RAB6, RAB6A
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P20340
Immunogen
Recombinant human Ras-related protein Rab-6A protein (2-208AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Ras-related protein Rab-6A
Literature
[1]”Rab6 family proteins interact with the dynein light chain protein DYNLRB1.” Wanschers B.F.J., van de Vorstenbosch R., Wijers M., Wieringa B., King S.M., Fransen J. Cell Motil. Cytoskeleton 65:183-196(2008). [2]”Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic.” Yamane J., Kubo A., Nakayama K., Yuba-Kubo A., Katsuno T., Tsukita S., Tsukita S. Exp. Cell Res. 313:3472-3485(2007). [3]”Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex.” Matanis T., Akhmanova A., Wulf P., Del Nery E., Weide T., Stepanova T., Galjart N., Grosveld F., Goud B., De Zeeuw C.I., Barnekow A., Hoogenraad C.C. Nat. Cell Biol. 4:986-992(2002).
