Aliases
dickkopf WNT signaling pathway inhibitor 1
Antibody Type
Polyclonal Antibody
Uniprot ID
O94907
Immunogen
Synthetic peptide of human DKK1
Raised In
Rabbit
Species Reactivity
Human, Mouse
Tested Applications
ELISA: 1:2000-1:5000; IHC: 1:25-1:100
Background / Function
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen affinity purification
