Aliases
solute carrier family 39 (zinc transporter), member 3
Antibody Type
Polyclonal Antibody
Uniprot ID
Q9BRY0
Immunogen
Synthetic peptide of human SLC39A3
Raised In
Rabbit
Species Reactivity
Human, Mouse, Rat
Tested Applications
ELISA: 1:1000-1:2000; IHC: 1:20-1:100
Background / Function
SLC39A3 (solute carrier family 39, member 2), is a 314 amino acid acid multi-pass membrane protein that localizes to the cell membrane and belongs to the ZIP family of zinc transporters. Two isoforms of ZIP3 exist as a result of alternative splicing events. ZIP3 is involved in translocation of extracellular zinc into a variety of cell types. Tumorigenic prostate epithelial cells contain less intracellular zinc than non-tumorigenic prostate epithelial cells. Loss of the ability to maintain zinc accumulation may be caused by the decrease in the ZIP1 protein expression and the intracellular redistribution of ZIP3.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen affinity purification
