Aliases
SLIT-ROBO Rho GTPase activating protein 2
Antibody Type
Polyclonal Antibody
Uniprot ID
O75044
Immunogen
Synthetic peptide of human SRGAP2
Raised In
Rabbit
Species Reactivity
Human, Mouse, Rat
Tested Applications
ELISA: 1:2000-1:5000; IHC: 1:25-1:100
Background / Function
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen affinity purification