Aliases
transcription elongation factor B polypeptide 3B (elongin A2)
Antibody Type
Polyclonal Antibody
Uniprot ID
Q8IYF1
Immunogen
Synthetic peptide of human TCEB3B
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA: 1:2000-1:10000; IHC: 1:30-1:150
Background / Function
This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen affinity purification
