Description
Aliases
REG-3-gamma, Pancreatitis-associated protein 3, Regenerating islet-derived protein III-gamma, Reg III-gamma, Pap3, Reg3g
Antibody Type
Polyclonal Antibody
Species
Rat
Uniprot ID
P42854
Immunogen
Recombinant rat Regenerating islet-derived protein 3-gamma protein (2-110AA)
Raised In
Rabbit
Species Reactivity
Rat,mouse
Tested Applications
ELISA, WB;Not yet tested in other applications.
Background / Function
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury (By similarity).
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Regenerating islet-derived protein 3-gamma
Literature
[1]”Reg3G gene expression in regenerating skeletal muscle and corresponding nerve.” Klasan G.S., Ivanac D., Erzen D.J., Picard A., Takasawa S., Peharec S., Arbanas J., Girotto D., Jerkovic R. Muscle Nerve 49:61-68(2014). [2]”Cloning, expression and chromosomal localization of the rat pancreatitis-associated protein III gene.” Dusetti N.J., Frigerio J.-M., Szpirer C., Dagorn J.-C., Iovanna J.L. Biochem. J. 307:9-16(1995). [3]”The pancreatitis associated protein III (PAP III), a new member of the PAP gene family.” Frigerio J.-M., Dusetti N.J., Garrido P., Dagorn J.-C., Iovanna J.L. Biochim. Biophys. Acta 1216:329-331(1993).Additional information
| Size | 50μg, 100μg |
|---|
