Aliases
90 kDa ribosomal protein S6 kinase 6; EC 2.7.1.37; EC 2.7.11.1; KS6A6; RPS6KA6
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q9UK32
NCBI Gene ID: 27330
Immunogen
Synthesized peptide derived from internal of human S6K-α6.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB IHC Recommended dilution: Western blotting: 1:500~1:3000, Immunohistochemistry: 1:50~1:100,
Background / Function
Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.Ross M.T., Nature 434:325-337(2005).Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.Yntema H.G., Genomics 62:332-343(1999).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.