Description
Aliases
CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CRACC, Membrane protein FOAP-12, Novel Ly9, Protein 19A, CD319, SLAMF7, CS1, UNQ576/PRO1138
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9NQ25
Immunogen
Recombinant human SLAM family member 7 protein (23-226AA)
Raised In
Rabbit
Species Reactivity
Human,Mouse
Tested Applications
ELISA, WB, IHC;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200
Background / Function
Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 does not mediate any NK cell activation.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
Literature
[1]Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors.” Tovar V., Del Valle J., Zapater N., Martin M., Romero X., Pizcueta P., Bosch J., Terhorst C., Engel P. Immunogenetics 54:394-402(2002). [2]Molecular and functional characterization of a CS1 (CRACC) splice variant expressed in human NK cells that does not contain immunoreceptor tyrosine-based switch motifs.”Lee J.K., Boles K.S., Mathew P.A.Eur. J. Immunol. 34:2791-2799(2004). [3]Signal peptide prediction based on analysis of experimentally verified cleavage sites.” Zhang Z., Henzel W.J.Protein Sci. 13:2819-2824(2004).Additional information
| Size | 50μl, 100μl |
|---|
