Aliases
adenine nucleotide translocator 2; adenine nucleotide translocator 3; ADP; ATP carrier 3; ADP
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P12236
NCBI Gene ID: 293
Immunogen
Synthesized peptide derived from internal of human SLC25A6.
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000
Background / Function
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.Cozens A.L., J. Mol. Biol. 206:261-280(1989).Zhou J., Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.Houldsworth J., Proc. Natl. Acad. Sci. U.S.A. 85:377-381(1988).
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.