SMCC (Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate )

Description

General Description

SMCC is Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate, a non-cleavable, heterobifunctional and membrane permeable crosslinker, which contains an amine-reactive N -hydroxysuccinimide (NHS ester) and a sulfhydryl-reactive maleimide group. NHS esters react with primary amines at pH 7-9 to form stable amide bonds and Maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds.

Molecular formula:      C16H18N2O6

Molecular Weight:       334.32

CAS name/number:     64987-85-5

Spacer Arm:                  8.3 Å

Additional information