General Description
SMPB is Succinimidyl 4-(p-maleimidophenyl)Butyrate, a heterobifunctional crosslinkers that contain N-hydroxysuccinimide (NHS) ester and maleimide reactive groups that permit covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at alkaline pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at acidic pH 6.5-7.5 to form stable thioether bonds.
Â
Molecular Weight:Â Â 356.33
Spacer Arm:Â Â Â Â Â Â Â Â 11.6Ã…
Features of SMPB:
1. Reactive groups: NHS ester and maleimide
2. Reactive towards: amino and sulfhydryl groups
3. Non-cleavable
![IEF Cathode Buffer (pH 3-7) [10X]](https://www.cephamls.com/wp-content/uploads/2019/02/10498-3-430x334.jpg)
