Description
Aliases
Signal transducer and activator of transcription 5B; STA5B; STAT5; transcription factor STAT5B;
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: P42230/P42232;
NCBI Gene#: 20850
Immunogen
Peptide sequence around phosphorylation site of serine725/730(A-P-S(p)-P-V) derived from Human STAT5A/B.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:1000
Background / Function
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription. Ross JA, et al. (2010) J Biol Chem 285, 3582-91 Uddin S, et al. (2003) Biochem Biophys Res Commun 308, 325-30Xue HH, et al. (2002) Int Immunol 14, 1263-71
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Ser725/730
Additional information
| Size | 100?l |
|---|
