Aliases
STMN1; STN1; stathmin
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: P16949
NCBI Protein: NP_001138926.
Immunogen
Peptide sequence around aa.60~64 (R-K-S-H-E) derived from Human Stathmin 1.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC Recommended dilution: Predicted MW: 19kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,
Background / Function
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear Marklund, U. et al. (1994) Eur. J. Biochem. 225, 53-60.Gavet, O. et al. (1998) J. Cell Sci. 111, 3333-3346.Di Paolo, G. et al. (1996) J. Cell. Biol. 133, 1383-1390.
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
